The film is a music video set to an original song - "It's Good to Have a Change of Heart".

It explains the science of heart failure through the story of Dan, a drummer in a band called "The H Beats". Heart failure is starting to affect Dan's performance. Seeing this, a compassionate friend takes him on a journey to learn about the condition and how ENTRESTO can help. In keeping with the theme of change, every time the chorus hits, the animation style changes. We go from 2-D to CGI, to paper, wood and clay texture styles.

By the end, Dan's beat is restored - a change of heart made possible by a medicine that's changing heart failure treatment.

We wrote what is probably the first song in history about the science of heart failure.

We used words like Valsartan and Sacubitril and actually made them scan.

We wrote lyrics about relaxing blood vessels so more blood flows through

And we found a singer who actually made those scientific words sound beautiful.

Most importantly, we developed a strong hook line for the chorus: "It's good to have a change of heart"

Our composer set those words to an equally memorable melody.

Odds are, you'll be humming it after you watch the video.

Branded pharma content in the US is strictly regulated as is content on Youtube. Per regulations, our two minute method of action video is followed by more than 3 minutes of scrolling safety information.

Our target is patients who've been diagnosed with heart failure and those who will be (1 in 5 people will develop heart failure in their lifetime). Heart failure is a serious condition that's often misunderstood. Education is sorely needed.